Persistent neonatal hypoglycaemia due to glucagon deficiency.
نویسندگان
چکیده
In a newborn baby, suffering from persistent severe hypoglycaemia with convulsions glucagon deficiency was shown. Treatment with zinc-protamine-glucagon injection twice daily resulted in normal blood glucose levels. Motor development is delayed.
منابع مشابه
Prevention and management of neonatal hypoglycaemia.
1 Hill DJ, Milner RDG. Insulin as a growth factor. Pediatr Res 1985; 19: 879-86 2 Hill DE. Effect of insulin on fetal growth. Semin Perinatol 1978; 2: 319-28. 3 Srinivasan G, Pildes RS, Cattamanchi G, Voora S, Lilien LD. Plasma glucose values in normal neonates: a new look. _J Pediatr 1986; 109: 114-7. 4 Padbury JF. Functional maturation of the adrenal medulla and peripheral sympathetic nervous...
متن کاملSustained Liver Glucose Release in Response to Adrenaline Can Improve Hypoglycaemic Episodes in Rats under Food Restriction Subjected to Acute Exercise
Background. As the liver is important for blood glucose regulation, this study aimed at relating liver glucose release stimulated by glucagon and adrenaline to in vivo episodes of hypoglycaemia. Methods. The blood glucose profile during an episode of insulin-induced hypoglycaemia in exercised and nonexercised male Wistar control (GC) and food-restricted (GR, 50%) rats and liver glucose release ...
متن کاملHepatic glycogen synthetase deficiency
In the 13 years since hepatic glycogen synthetase deficiency was first described in identical twins no further cases seem to have been observed. We report a child who had suffered from occasional morning convulsions since the age of 7. Three 24-hour metabolic profiles showed fasting hypoglycaemia, hyperketonaemia, but normal lactate. Hyperglycaemia and hyperlactataemia occurred after meals. Glu...
متن کاملNeonatal hypoglycaemia: an important early sign of endocrine disorders.
The incidence of hypoglycaemia is greatest in the neonatal period, and the condition is usually associated with "small for dates" infants, although rare causes have been described.' Persistent neonatal hypoglycaemia, however, is usually caused by endocrinopathies or disorders of hepatic metabolism.2 We present some ofour experience of endocrine disease presenting as neonatal hypoglycaemia as th...
متن کاملDeath within the first 24 hours of admission among newborn infants aged less than 24 hours in a Nigerian Special Care Baby Unit: Role of significant hypothermia and hypoglycaemia
Background: Neonatal deaths mostly occur within the first one week and first 24 hours of life from a variety of conditions. Objective: To examine the role of significant hypothermia and hypoglycaemia, in addition to some other factors, in neonatal mortality occurring within the first 24 hours of admission.Methods: A prospective study of newborn infants hospitalized within the first 24 hours of ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Archives of disease in childhood
دوره 53 5 شماره
صفحات -
تاریخ انتشار 1978